Making the Connections: A How-To Guide for Organic Chemistry Lab Techniques

Anne B. Padías | Fourth Edition

Item Number: v328083 Availability: Out of stock ISBN: 978-1-64565-215-1

Description

We are excited to share with you the new fourth edition of Making the Connections. If you are familiar with any of the previous versions, you are aware of the approach, connecting students’ existing knowledge to the situation they are stepping into, the organic lab. And even though there have been plenty of changes since our last edition, we have remained true to this methodology. Many of our examples are designed to bridge that gap between what students know now and what they are learning. Another theme we have maintained with this edition is our careful and detailed explanations often pairing them with four-color illustrations on how to safely perform the essentials of basic lab work. While we can’t cover every scenario and lab set-up, we start out with safety on the first page and return to it throughout the entire book. We understand that dangers lurk in an organic lab, and require vigilance, knowledge, and common sense to avoid them. As we wrote in the previous edition, when you are in a chemistry building, everyone should be attentive to the potential hazards.

If you are new to our book or considering it for your students, thank you for making the time to review. If you have questions or have ideas for improving the book, please reach out to us at info@van-griner.com. We always welcome the feedback.

Finally, I would like to thank Josh Osbourn and Brian Nichols at West Virginia University for their assistance with the revision. Dedicated instructors, their insight into today’s students and the changes occurring in the field provided valuable contributions to this edition.

Chapter 1 – First, the Basics

Chapter 2 – How to Identify Compounds

Chapter 3 – Purification Techniques

Chapter 4 – Running a Reaction

Glossary

Index

An updated design, including:

    • four-color internals
    • new illustrations

An eBook format available

 

4th Edition Content Updates

Chapter 1 – First, the Basics

  • The section on hazardous chemicals has been updated to include the HCS (Hazardous Communication Standard) for container labeling along with the inclusion of HCS pictograms for identifying hazards.
  • The sample laboratory notebook has been completely revised and rewritten. The new version contains several callouts to guide students on proper notebook keeping techniques.
  • Useful equations and calculations have been emphasized with color/callouts to make them easier to identify.
  • A dedicated 2-page spread of common organic glassware with pictures has been included to provide a quick visual reference to students who are getting started in the organic laboratory.
  • A solvent miscibility chart is now included with a discussion of miscible and immiscible solvent systems. This chart is referred to when discussing mixed solvents in extraction, distillation, and chromatography.

Chapter 2 – How to Identify Compounds

  • Chemical reference information/databases have been updated to remove out-of-print publications and to include modern resources such as SciFinder and Reaxys.
  • The IR section has been updated to include modern ATR-FTIR instruments.
  • The section on IR interpretation has been completely rewritten to provide a comprehensive guide to analyzing an IR spectrum for each of the common functional groups. Several new IR spectra have been included to illustrate the functional group absorptions. The IR spectra are now labeled to include the structure and have the functional groups and corresponding absorptions highlighted on the spectrum for easy analysis.
  • The section on NNMR spectrometry has been rewritten for improved organization.
  • The 1H NMR spectra have all been revised and now include the chemical structure overlaid on the spectrum.
  • A step-by-step analysis of a 1H NMR spectrum from identifying chemical shifts, integration, multiplicity, to coupling constants is now included. Pedagogically, this is presented in such a way that the student builds a table of chemical shift data that can be included in their lab notebook or lab report.
  • An all-new colorful chemical shift table is now included in the text and on the inside cover of the book.
  • The tables of 1H NMR coupling constants have been updated to include aromatic proton coupling constants.
  • A small section on calculating the degree of unsaturation from a molecular formula has been added for quick reference.
  • All new 1H NMR interpretation examples have been included.
  • A new section on recording and reporting NMR data has been included. This section describes how to report NMR data in paragraph form for inclusion in a publication.
  • In the mass spectrometry section, the fragmentation pattern of n-octant has been updated to include a graphical representation of the various cation and radical fragments that appear.

Chapter 3 – Purification Techniques

  • A section containing methods to induce crystallization has been added.
  • An expanded discussion of using mixed solvent systems for crystallization is now included.
  • The section on azeotropic distillation has been revised for clarity.
  • In the section on chromatography, a discussion and chart of functional group polarity are now included. A table of the eluotropic series is also included to help students choose solvents of the appropriate polarity to perform a chromatographic separation.
  • A new section with commonly encountered TLC issues (streaking, bleeding, overloaded plate, etc.) and potential solutions is now included.

Chapter 4 – Running a Reaction

  • Running a Reaction has been reorganized and expanded into seven sections that guide the student from start to finish in running a chemical reaction and analyzing the products.
  • The section on Green Chemistry has been expanded to include the 12 Principles of Green Chemistry along with examples of how these principles can be utilized in a synthetic laboratory.

End of Chapter Problems

  • New End of Chapter Problems will be included for each chapter with instructor provided solutions.

Glossary

  • A glossary will be added to the back of the book to allow students to quickly look up unfamiliar terms.

Solutions Manual

LabRight is an online, customizable platform for lab manuals. It can be used with our book, your materials or Van-Griner’s existing labs to create the perfect pre-, in- or post-lab experience. Completely set-up and supported by Van-Griner, it is easily integrated into your LMS for help with grading, student preparation and TA management. To learn more, sign up for a demo at labrightlearning.com.

Anne Padías received her Ph.D. in chemistry from the State University of Ghent in 1975. She did her postdoctoral work at the University of Arizona with Prof. H. K. Hall, Jr., and spent the next 35 years at that institution. For over 20 of those years, she coordinated the labs, leading to the writing of this book. Her favorite thing about chemistry is the connection between what happens in the lab with what happens in real life: there’s always a real-life application for chemistry.